Asymmetric total synthesis of ent-heliespirones A & C.
نویسندگان
چکیده
A concise 8-step synthetic route toward ent-heliespirones A & C is described. This synthetic strategy features a highly diastereoselective palladium-catalyzed Michael addition to form 3,5-trans lactone and a final biomimetic intramolecular oxa-spirocyclization.
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عنوان ژورنال:
- Chemical communications
دوره 46 29 شماره
صفحات -
تاریخ انتشار 2010